Begin by juicing your blood oranges and limes. To make the margarita mix, combine the blood orange juice, lime juice, tequila, orange liqueur, and simple syrup in a small pitcher. Taste, and add more simple syrup, alcohol, or juice as necessary. Refrigerate until you’re ready to serve.

To assemble the margaritas, place about 2 Tablespoons of margarita salt or sugar on a plate, and gently tap the plate to spread it out. Rub the rim of four margarita glasses with a wedge of lime. Press the rim of the glasses into the salt or sugar to ensure an even coat. Fill each glass with ice, and add 5.25 ounces of the margarita mix. Garnish with a blood orange wedge or lime wedge if desired. Serve immediately.